It took me awhile to find this one. When I start Radio it tries to open a web page at 127.0.0.1:5335. If I tried localhost:5335 it worked. For some reason the ISA firewall was getting the request. Naturally it refused to allow me to do it. It didn't know any better but it shouldn't have been involved. I never had to do this before but I had to code 127.0.0.1 into the ISA client configuration for the web browser and hard code 127.0.0.1 as a site I could go directly to and then reboot my client workstation. I think this is a result of my change to using automatic configuration.